自制处方日粮和西葫芦对成年猫尿液的草酸钙过饱和度与尿液指标的有益影响

期号：Vol 24, Issue 10, February 10, 2022

作者：Géraldine Blanchard，Concetta Amato，Agnès André，Philippe Bleis，Samuel Ninet，Jürgen Zentek，Patrick Nguyen 

摘要来源：

https://doi.org/10.1177/1098612X211067931

译员：Joey

一校：泡泡村

二校：朵曜腾

编辑：百可事乐

摘要

根据作者的经验，食用西葫芦（zucchini/courgette）及含西葫芦的自制均衡处方日粮对复发性尿石症患猫有益，目前尚无已发表的证据支持这一观点。因此，本研究的目的将（1）含西葫芦的自制均衡处方日粮；（2）在干粮中添加西葫芦与两种市售处方日粮进行比较，观察不同食物对尿液指标的影响。

根据拉丁方设计（Latin square design）流程，本研究共纳入8只健康的猫。本研究评估了五种日粮，包括：两种市售的泌尿系统疾病患猫的处方粮，一种是高水分湿粮（U-WET）、另一种是高钠干粮（U-DRY）；一种自制日粮（HOME）；一种市售的成年猫维持干粮（DRY）；最后一种是根据动物的体重按10 g/kg在DRY中添加西葫芦（DRY-Zuc）的粮食。经过7天适应性饲喂后，收集猫的尿液并评估之后12天中每日食物和水的摄入量。测定尿液指标，以及草酸钙（CaOx）和鸟粪石的相对过饱和度（relative supersaturation，RSS）。结果数据进行重复测量方差分析。

HOME的能量、干物质、蛋白质和脂肪的可消化性最高。食用HOME猫的CaOx RSS最低，但与食用U-WET或U-DRY的猫之间无显着差异。食用DRY-Zuc猫的CaOx RSS低于食用DRY的猫。各组间鸟粪石RSS无显着差异。

本研究表明，均衡的自制处方日粮是安全的，食用该日粮的猫其尿液CaOx RSS非常低。本项研究还表明，在干粮中加入西葫芦能够降低尿液CaOx RSS。

关键词：水的摄入量，膳食钠，尿比重，高蛋白，自制饮食，酸碱度，相对过饱和度

原文：

Beneficial effects of a prescription home-prepared diet and of zucchini on urine calcium oxalate supersaturation and urinary parameters in adult cats

Géraldine Blanchard，Concetta Amato，Agnès André，Philippe Bleis，Samuel Ninet，Jürgen Zentek，Patrick Nguyen 

https://doi.org/10.1177/1098612X211067931

Abstract

Objectives

From the authors’ experience, the consumption of a balanced prescription home-prepared diet that includes zucchini (courgette) benefits cats with recurrent urolithiasis, but there is no published evidence to support this. The aim was to study the effects on urinary parameters of (1) a balanced prescription home-prepared diet containing zucchini, and (2) the addition of zucchini to a dry food, compared with two commercial therapeutic diets.

Methods

Eight healthy cats were included in a Latin-square designed protocol. Five diets were evaluated: two commercial diets, designed for cats with urinary disorders, one high-moisture (U-WET) and one high-sodium dry (U-DRY); one home-prepared diet (HOME); one commercial dry food for adult maintenance (DRY); and DRY given together with 10 g of zucchini per kg body weight (DRY-Zuc). After a 7-day adaptation period, urine was collected and daily food and water intakes were assessed for 12 days. Urinary parameters, and relative supersaturation (RSS) for calcium oxalate (CaOx) and struvite, were determined. Data underwent repeated measures ANOVA analysis.

Results

The digestibility of energy, dry matter, protein and fat was highest with the HOME diet. CaOx RSS was lowest in cats eating the HOME diet, but not significantly different from the U-WET or U-DRY diets. CaOx RSS was lower in cats eating the DRY-Zuc diet than in cats eating the DRY diet. Struvite RSS did not differ significantly among groups.

Conclusions and relevance

This study shows that a balanced prescription home-prepared diet was safe and allowed a very low urinary CaOx RSS. It also showed that adding zucchini to dry food lowered the urine CaOx RSS.

Keywords

Water intake; dietary sodium; gravity; high-protein; home-prepared diet; pH; relative supersaturation